Author

Javier De Vicente

Denali Therapeutics (United States)ORCID 0000-0001-7578-5330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anastasia G. HenryiD· 1 shared Annie ArguelloiD· 1 shared Anthony A. EstradaiD· 1 shared Audrey Cheuk-Nga Ho· 1 shared Chi‐Lu Chiu· 1 shared David J. VocadloiD· 1 shared Gilbert Di PaoloiD· 1 shared Giuseppe AstaritaiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Anastasia G. HenryORCID

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1 paper

Recent·Most cited

NeuroscienceMolecular NeurodegenerationPeer-reviewedAug 6, 2025

LRRK2 Kinase Activity Regulates Parkinson's Disease-Relevant Lipids at the Lysosome

Michael T. Maloney, Xiang Wang, Rajarshi Ghosh…·Anastasia G. Henry

This study shows that LRRK2 kinase activity affects BMP and GSL levels in lysosomes, linking lysosomal dysfunction to Parkinson's disease through changes in GCase activity and BMP accumulation.

18 citationstop 2%

humanexperimental assay

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