Author

Malcolm Buckle

Centre National de la Recherche ScientifiqueORCID 0000-0001-7596-3467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:comparative / phylogenetic analysis· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Akiko HatakeyamaiD· 1 shared Ashley M. BuckleiD· 1 shared Benjamin T. PorebskiiD· 1 shared Brigitte HartmanniD· 1 shared Claude NoguèsiD· 1 shared Cyril F. RebouliD· 1 shared Daniel ChristiD· 1 shared Daniel E. WilliamsiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Akiko HatakeyamaORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMar 7, 2025

Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11

Susanne H. D. Ständer, Cyril F. Reboul, Sarah N. Le…·Ashley M. Buckle

This study characterizes the structure and dynamics of GAD65 and its interaction with autoantibody b96.11, revealing how intrinsic conformational flexibility drives autoantigenicity.

10 citations

humanstructural biology

𝕏 PostBluesky

Molecular BiologybioRxivPreprintApr 1, 2020

Nucleosome assembly and disassembly pathways.

Akiko Hatakeyama, Romain Retureau, Marco Pasi…·Malcolm Buckle

This paper uses PhAST to compare nucleosome assembly and disassembly, revealing structural asymmetry and intermediate states not observed in previous studies.

DOI 10.1101/2020.04.01.020263

experimental assay

𝕏 PostBluesky