Vasimuddin Md

This work optimizes whole-genome alignment for multi-core processors, improving speed by 1.6x to 7.2x across human, plant, and primate genomes without sacrificing accuracy.

The paper optimizes minimap2 for faster long-read mapping on CPUs, achieving up to 1.8x speedup without changing output.

The paper introduces LISA, a machine learning-based index for accelerating sequence search in genomics, showing performance improvements over traditional indexes in various case studies.

The paper identifies four computational building blocks that dominate runtime in NGS secondary analysis tools across sequence mapping, de novo assembly, and variant calling.