Dual nuclease single-cell lineage tracing by Cas9 and Cas12a
Cheng Chen, Yuanxin Liao, Miao Zhu, Li Wang, Xinran Yu, Meishi Li, Guangdun Peng
DuTracer improves single-cell lineage tracing by using two CRISPR systems to record deeper and more accurate lineage histories with reduced barcode dropout.
Cell Reports · Dec 24, 2024Peer-reviewedDevelopmental Biology