Li Wang

The gut microbiota enhances translation of innate barrier defense proteins through HDAC5-mediated activation of mTORC1 signaling.

DuTracer improves single-cell lineage tracing by using two CRISPR systems to record deeper and more accurate lineage histories with reduced barcode dropout.

The paper maps spatial and molecular changes in germ layers during primate gastrulation using spatial transcriptomics and 3D modeling.

The paper systematically characterizes short intronic splicing-regulatory elements by analyzing their effects on exon splicing using a minigene approach.

iSMNN improves batch effect correction in scRNA-seq by iteratively refining mutual nearest neighbors, enhancing cell type mixing and differential gene identification across batches.