Characterizing the Ion-Conductive State of the α7-Nicotinic Acetylcholine Receptor via Single-Channel Measurements and Molecular Dynamics Simulations
Nauman Sultan, Gisela D. Cymes, Ada Y. Chen, Bernard R. Brooks, Claudio F. Grosman, Ana Damjanovic
This study combines single-channel recordings and MD simulations to evaluate the conductive properties of different 7-nAChR structures, identifying which conformations align with physiological function.
The Journal of Physical Chemistry B · Feb 6, 2026Peer-reviewedBiophysics