Author

Hao-Yu Zhang

University College LondonORCID 0000-0001-7642-6831Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:long-read sequencing· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher J. MinnisiD· 2 shared Emil Karl GustavssoniD· 2 shared Mina RyteniD· 2 shared Sara MoleiD· 2 shared Andrew R. WebsteriD· 1 shared Angela SchulziD· 1 shared Claire AndersoniD· 1 shared Emily GardneriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Christopher J. MinnisORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 24, 2025

Targeted long-read RNA sequencing reveals the complexity of CLN3 transcription and the consequences of the most common 1-kb deletion in patients with juvenile CLN3 disease

Christopher J. Minnis, Hao-Yu Zhang, Emil Karl Gustavsson…·Sara Mole

The paper uses long-read RNA sequencing to analyze CLN3 transcription complexity and the impact of a common 1-kb deletion in juvenile CLN3 disease, revealing multiple transcripts and isoforms.

DOI 10.1101/2025.04.24.650398

humanlong-read sequencing

𝕏 PostBluesky

GeneticsbioRxivPreprintOct 12, 2023

CLN3 transcript complexity revealed by long-read RNA sequencing analysis

Hao-Yu Zhang, Christopher J. Minnis, Emil Karl Gustavsson…·Sara Mole

The paper uses long-read RNA sequencing to analyze CLN3 transcript complexity in healthy samples, identifying over 100 novel transcripts and 48 ORFs, with the canonical isoform being the most abundant.

1 citation

humanlong-read sequencing

𝕏 PostBluesky