Ellen M. Quardokus

The paper presents tools to validate and simplify ontology term hierarchies for better usability in biomedical research.

The paper analyzes endothelial cell environments across organs using spatially resolved omics data and provides an interactive tool for visualizing cell distances and neighborhoods.

The paper introduces the Human Reference Atlas Knowledge Graph, a large-scale linked data resource for biological entities, and describes its construction, deployment, and usage.

The paper introduces a comprehensive catalog of 22 functional tissue units (FTUs) in 10 healthy human organs, detailing their anatomy, vasculature, and cellular composition.

The paper evaluates five algorithms for segmenting functional tissue units in kidney and colon tissues using histological stains, comparing their accuracy and generalizability.

This paper introduces the Common Coordinate Framework Ontology (CCFO) v2.0.1 to integrate specimen, biological structure, and spatial data for the Human Reference Atlas, enabling interoperability and programmatic access.

The paper presents software tools and user interfaces for annotating and exploring tissue data in a human reference atlas, enabling data harmonization and public access.