Author

Samuel Rosean

Albert Einstein College of MedicineORCID 0000-0001-7695-2540Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Evolutionary Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Cathal SeoigheiD· 2 shared Dónal O’SheaiD· 2 shared Eric SosaiD· 2 shared John M. GreallyiD· 2 shared Aviv BergmaniD· 1 shared Caroline Yoon· 1 shared Jacob StauberiD· 1 shared Melissa J. FazzariiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Cathal SeoigheORCID

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3 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintAug 11, 2026

No Trade-Offs Required: Cross-Feeding From Survival Alone

Samuel Rosean, Aviv Bergman

This paper shows that cross-feeding in microbial communities can evolve from energy acquisition alone, without requiring specific metabolic trade-offs or exchange mechanisms.

DOI 10.64898/2026.08.07.743543

deep learningstatistical model

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintSep 23, 2025

Individuals with intellectual disability have an increased burden of de novo variants in cis-regulatory elements of glutamatergic neurons.

Eric Sosa, Dónal O’Shea, Samuel Rosean…·John M. Greally

DOI 10.1101/2025.09.23.25336266

humanwhole-genome sequencing

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BioinformaticsbioRxivPreprintOct 11, 2023

Regulatory Landscape Enrichment Analysis (RLEA) using gaiaAssociation

Eric Sosa, Samuel Rosean, Dónal O’Shea…·John M. Greally

The paper introduces gaiaAssociation, a tool for Regulatory Landscape Enrichment Analysis (RLEA) to identify cell types mediating phenotypes from GWAS data by testing locus enrichment in cell type-specific open chromatin regions.

DOI 10.1101/2023.10.11.561933

ChIP-seqstatistical model

𝕏 PostBluesky