Cell BiologyJournal of Theoretical BiologyPeer-reviewed
Understanding the regulation of chronic wounds by tissue inhibitors of matrix metalloproteinases through mathematical modelling
Sonia Dari, Reuben D. O’Dea, Nabil T. Fadai
The paper develops a mathematical model of wound healing dynamics to show that deregulated apoptosis and low TIMP production lead to chronic wounds, and that TIMP-containing hydrogels can reverse them.
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