Author

Amanda McGovern

University of ManchesterORCID 0000-0001-7727-3283Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:Hi-C· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Antony D. AdamsoniD· 3 shared Kate DuffusiD· 3 shared Magnus RattrayiD· 3 shared Paul MartiniD· 3 shared Stephen EyreiD· 3 shared Andrew P. MorrisiD· 2 shared Annie YarwoodiD· 2 shared Chenfu ShiiD· 2 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Antony D. AdamsonORCID

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4 papers

Recent·Most cited

Developmental BiologybioRxivPreprintSep 19, 2025

Decoding the Spatial and Epigenetic Logic of Early Skin Development

Nigel L. Hammond, Syed Murtuza Baker, Amanda McGovern…·Michael James Dixon

This study identifies gene regulatory networks driving periderm formation in early skin development using single-cell multiome and spatial transcriptomics data.

1 citation

mousescRNA-seq

𝕏 PostBluesky

GenomicsJournal of Investigative DermatologyPeer-reviewedFeb 17, 2021

An active chromatin interactome in relevant cell lines elucidates biological mechanisms at genetic risk loci for dermatological traits

Chenfu Shi, Helen F. Ray-Jones, James Ding…·Gisela Orozco

The paper identifies gene targets at risk loci for skin-related disorders by integrating HiChIP data from relevant cell lines and public datasets.

32 citations

humanHi-C

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GenomicsNature CommunicationsPeer-reviewedSep 2, 2020

Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis

Jing Yang, Amanda McGovern, Paul Martin…·Stephen Eyre

71 citations

humanATAC-seq

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GenomicsbioRxivPreprintOct 31, 2019

Chromatin-based techniques map DNA interaction landscapes in psoriasis susceptibility loci and highlight KLF4 as a target gene in 9q31

Helen F. Ray-Jones, Kate Duffus, Amanda McGovern…·Stephen Eyre

This study uses Capture Hi-C and CRISPR activation to identify KLF4 as a target gene in the 9q31 psoriasis risk locus, linking GWAS variants to functional interactions.

DOI 10.1101/822304

humanChIP-seq

𝕏 PostBluesky