Author

Kate Duffus

University of ManchesterORCID 0000-0002-8925-1863Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Amanda McGoverniD· 3 shared Paul MartiniD· 3 shared Stephen EyreiD· 3 shared Andrew P. MorrisiD· 2 shared Annie YarwoodiD· 2 shared Antony D. AdamsoniD· 2 shared Chenfu ShiiD· 2 shared Gisela OrozcoiD· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Amanda McGovernORCID

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3 papers

Recent·Most cited

An active chromatin interactome in relevant cell lines elucidates biological mechanisms at genetic risk loci for dermatological traits

Chenfu Shi, Helen F. Ray-Jones, James Ding, Kate Duffus, Yao Fu, Vasanthi Priyadarshini Gaddi, Oliver Gough, Jenny Hankinson, Paul Martin, Amanda McGovern, Annie Yarwood, Patrick M. Gaffney, Stephen Eyre, Magnus Rattray, Richard Bruce Warren, Gisela Orozco

The paper identifies gene targets at risk loci for skin-related disorders by integrating HiChIP data from relevant cell lines and public datasets.

Journal of Investigative Dermatology · Feb 17, 2021Peer-reviewedGenomics

Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis

Jing Yang, Amanda McGovern, Paul Martin, Kate Duffus, Xiangyu Jack Ge, Peyman Zarrineh, Andrew P. Morris, Antony D. Adamson, Peter Fraser, Magnus Rattray, Stephen Eyre

Nature Communications · Sep 2, 2020Peer-reviewedGenomics

Chromatin-based techniques map DNA interaction landscapes in psoriasis susceptibility loci and highlight KLF4 as a target gene in 9q31

Helen F. Ray-Jones, Kate Duffus, Amanda McGovern, Paul Martin, Chenfu Shi, Jenny Hankinson, Oliver Gough, Annie Yarwood, Andrew P. Morris, Antony D. Adamson, Christopher J. Taylor, James Ding, Vasanthi Priyadarshini Gaddi, Yao Fu, Patrick M. Gaffney, , Stephen Eyre

This study uses Capture Hi-C and CRISPR activation to identify KLF4 as a target gene in the 9q31 psoriasis risk locus, linking GWAS variants to functional interactions.

bioRxiv · Oct 31, 2019 · PreprintGenomics