GeneticsbioRxivPreprint
An Optimally Weighted Combination Method to DetectNovel Disease Associated Genes Using Publicly Available GWAS Summary Data
Jianjun Zhang, Samantha Gonzales, Jianguo Liu…·Xuexia Wang
The paper introduces an optimal weighted combination test for detecting novel disease-associated genes using GWAS summary data and shows it outperforms existing methods in simulations and real data.