Author

Jiafen Gong

Hospital for Sick ChildrenORCID 0000-0001-7760-1291Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:fine-mapping· 2 Research Focus:GWAS / association mapping· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Lisa J. StrugiD· 4 shared Scott MastromatteoiD· 4 shared Naim PanjwaniiD· 3 shared Anat HalevyiD· 2 shared Angela Chen· 2 shared Bhooma ThiruvahindrapuramiD· 2 shared Felix A. RatjeniD· 2 shared Joe WhitneyiD· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetics

Lisa J. StrugORCID

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4 papers

Recent·Most cited

GeneticsbioRxivPreprintMar 28, 2022

High Quality Phasing Using Linked-Read Whole Genome Sequencing of Patient Cohorts Informs Genetic Understanding of Complex Traits

Scott Mastromatteo, Angela Chen, Jiafen Gong…·Lisa J. Strug

The paper uses linked-read sequencing to phase alleles in 477 CF patients, revealing haplotypes that explain disease mechanisms and contribute to understanding complex traits.

1 citation

humanwhole-genome sequencing

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Genetic & Genomic MedicinemedRxivPreprintMar 28, 2022

A cystic fibrosis lung disease modifier locus harbors tandem repeats associated with gene expression

Delnaz Roshandel, Scott Mastromatteo, Cheng Wang…·Lisa J. Strug

The paper identifies VNTRs near SLC9A3 associated with gene expression in CF nasal epithelia and shows their utility in explaining GWAS signals.

DOI 10.1101/2022.03.28.22272580

humanlong-read sequencing

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GenomicsPLoS Computational BiologyPeer-reviewedOct 22, 2020

LocusFocus: A web-based colocalization tool for the annotation and functional follow-up of GWAS

Naim Panjwani, Fan Wang, Cheng Wang…·Lisa J. Strug

LocusFocus is a web tool that tests colocalization between GWAS and eQTL data to identify relevant genes and tissues for GWAS loci.

42 citations

GWAS summary statisticsstatistical model

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GeneticsBioinformaticsPeer-reviewedSep 26, 2019

VIKNGS: A C++ VARIANT INTEGRATION KIT FOR NEXTGENERATION SEQUENCING ASSOCIATION ANALYSIS

Zeynep Baskurt, Scott Mastromatteo, Jiafen Gong…·Lisa J. Strug

VIKNGS integrates NGS data for genetic association analysis, providing tools to adjust for differential genotype uncertainty and improve statistical power.

5 citations

whole-exome sequencingwhole-genome sequencing

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