Synthetic BiologybioRxivPreprint
Discrete-to-analog signal conversion in human pluripotent stem cells
Laura Prochazka, Yale S. Michaels, Charles Lau…·Peter W. Zandstra
The paper develops synthetic gene circuits in human pluripotent stem cells that convert discrete cell states into analog signals by integrating miRNAs with miSFITs for controlled effector protein production.
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