Author

Annette Aichem

Institute of Cell Biology and Immunology ThurgauORCID 0000-0001-7765-2160Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Charlotte WeissiD· 2 shared Guinevere MathiesiD· 2 shared Nicola Catone· 2 shared Alexander B. BarnesiD· 1 shared Barbara PerroneiD· 1 shared Sarah A. OveralliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

Charlotte WeissORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Biomolecular NMRPeer-reviewedAug 4, 2026

Co-sedimentation is the key to the structural investigation of wild-type FAT10

Charlotte Weiss, Barbara Perrone, Nicola Catone…·Guinevere Mathies

This study uses MAS NMR to investigate the wild-type FAT10 N-domain in complex with NUB1L, showing co-sedimentation improves spectral quality and reveals structural insights.

DOI 10.1007/s10858-026-00495-0

proteomicsmicroscopy & imaging analysis

BiochemistryJournal of the American Chemical SocietyPeer-reviewedMay 20, 2026

Intermolecular β-sheet formation guides the interaction between ubiquitin-like modifier FAT10 and adapter protein NUB1L

Charlotte Weiss, Sarah A. Overall, Nicola Catone…·Guinevere Mathies

The paper investigates the interaction between FAT10 and NUB1L using NMR spectroscopy, revealing that FAT10 adopts an intermolecular β-sheet upon binding, which stabilizes it in an unfolded state for proteasomal degradation.

2 citations

protein structureexperimental assay