Systems BiologyCirculation ResearchPeer-reviewed
A computational pipeline to predict cardiotoxicity:From the atom to the rhythm
Pei‐Chi Yang, Kevin R. DeMarco, Parya Aghasafari…·Colleen E. Clancy
This paper develops a multiscale computational model to predict cardiotoxicity from drug chemistry to cardiac rhythm, validated using clinical data and showing high predictive accuracy for arrhythmia vulnerability.
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