Florian Bénitière

This study shows that ciliates can break species barriers through recurrent horizontal gene transfer from highly divergent lineages, resulting in viable offspring.

gVCF2CNV converts gVCF files into CNV-compatible signals for large-scale WGS cohorts, achieving high precision in detecting deletions and duplications.

The paper develops FunBurd to analyze gene dosage effects on 43 traits in UK-Biobank, finding pleiotropy and non-monotonic responses linked to genetic constraint and brain-specific mechanisms.

MCNV2 assesses CNV quality using Mendelian Precision, offering tools to compute, explore, and optimize CNV call accuracy in parent-offspring trios.

The paper examines how gene dosage, polygenic background, and environment influence complex traits like height and BMI using large-scale data from multiple cohorts.

This study maps ASD genetic liability across cortical cell types using a functional genetic burden analysis of 124,416 individuals, showing developmentally dynamic liabilities and variant-specific contributions to different cell types.

The paper examines translational selection across 223 metazoan species, finding weak evidence of codon optimization in mammals and a correlation between population size and selection intensity.

The paper develops a method to analyze genomic deletions and duplications across the cerebral cortex and finds opposing effects on cognitive ability depending on gene expression patterns in different cortical regions.

GTDrift provides a resource analyzing genetic drift and genomic/transcriptomic features across 1,506 eukaryotic species, including life history traits, dN/dS ratios, and processed RNA-seq data for comparative studies.