Juri Kuronen

Mapping the evolutionary path towards multi-drug resistance in the pandemic Escherichia coli ST131 lineage

This study traces the evolutionary path from ST131-B to ST131-C clades in E. coli by analyzing genomic data from ST131-B0 isolates, revealing genetic changes associated with antibiotic resistance and host adaptation.

PAN-GWES: Pangenome-spanning epistasis and co-selection analysis via de Bruijn graphs

PAN-GWES identifies co-selected and epistatic genomic variations in bacterial genomes using de Bruijn graphs to analyze drug resistance and adaptation traits.

Genome-wide epistasis and co-selection study using mutual information

This paper introduces SpydrPick, a model-free method to detect co-selection and epistasis in bacterial genomes, revealing both known and novel targets in human pathogens.