Synthetic BiologybioRxivPreprint
Synergistic interactions between confinement and macromolecular crowding spatially order transcription and translation in cell-free expression
Sarah Elizabeth Norred, Rosemary M. Dabbs, Gaurav Chauhan…·Michael L. Simpson
This paper demonstrates that macromolecular crowding and confinement in cell-free systems can spatially organize transcription and translation, mimicking prokaryotic nucleoid behavior.
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