Author

Leon J. Schurgers

Maastricht UniversityORCID 0000-0001-7867-6957Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Christoph KuppeiD· 2 shared Hendrik MiltingiD· 2 shared Ivan G. CostaiD· 2 shared Junedh AmruteiD· 2 shared Karin KlingeliD· 2 shared Kory J. LavineiD· 2 shared Linda Wilhelmina Van LaakeiD· 2 shared Mingbo ChengiD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Christoph KuppeORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintFeb 14, 2026

Polyploid cardiomyocytes define disease-specific transcriptional states in the mammalian heart

Paul Kießling, Mehdi Joodaki, Daryna Pikulska…·Christoph Kuppe

This study identifies polyploid cardiomyocytes as disease-specific transcriptional states in the mammalian heart and suggests targeting them for heart failure treatment.

5 citations

humanrat

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Systems BiologyNaturePeer-reviewedAug 10, 2022

Spatial multi-omic map of human myocardial infarction

Christoph Kuppe, Ricardo O. Ramirez Flores, Zhijian Li…·Rafael Kramann

This study generates a high-resolution spatial multi-omic map of human myocardial infarction by integrating single-cell gene expression, chromatin accessibility, and spatial transcriptomic data to reveal cellular zones of injury, repair, and remodeling.

772 citationstop 1%

humanscRNA-seq

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