Author

Ashwini Kumar Sharma

ORCID 0000-0001-7883-7888Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Adrián CortésiD· 1 shared Daniel D. SeatoniD· 1 shared George Davey SmithiD· 1 shared Jimmy Z. LiuiD· 1 shared Jorge Esparza-Gordillo· 1 shared Laurence J HoweiD· 1 shared Neil M DaviesiD· 1 shared Philippe Sanséau· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Adrián CortésORCID

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1 paper

Recent·Most cited

GeneticsNature CommunicationsPeer-reviewedDec 13, 2025

Evaluating transportability of in-vitro cellular models to in-vivo human phenotypes using gene perturbation data

Laurence J Howe, Yurii S. Aulchenko, George Davey Smith…·Adrián Cortés

The paper evaluates the transportability of in-vitro gene perturbation models to in-vivo human phenotypes using CRISPR data and UK Biobank, finding some models are predictive while others are not.

1 citation

humanCRISPR screen

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