S. Eric Nybo

The paper develops a BioBricks genetic toolbox for metabolic engineering of the tetracenomycin pathway in Streptomyces coelicolor M1146 to produce analogs.

The paper determines and updates the sequences of two pIJ101-based Streptomyces-E. coli shuttle vectors, pEM4 and pUWL201, revealing discrepancies in their reported sizes.

This study develops a targeted metabolomics approach using LC/MS/MS and LC/Q-TOF/MS to quantify purine metabolites in cultured cells, integrating automated label-free microscopy for normalization.

This paper reports the metabolic engineering of Escherichia coli to produce valerenadiene, achieving 62.0 mg/L with optimized promoters and pathways.