Unsupervised learning of structural variability in cryo-EM data using normal mode analysis of deformable atomic models
Youssef S. G. Nashed, Julien Martel, Ariana Peck…·Frédéric Poitevin
The paper introduces an unsupervised method to analyze structural variability in cryo-EM data by deforming atomic models using normal mode analysis directly against 2D data, improving accuracy and interpretability.