Author

Otto Seppälä

Universität InnsbruckORCID 0000-0001-7902-3069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Katri Seppälä· 2 shared Ben AshbyiD· 1 shared Coen M. AdemaiD· 1 shared Dunja K. LamatschiD· 1 shared Jean‐Claude WalseriD· 1 shared Maurine NeimaniD· 1 shared Teo Cereghetti· 1 shared Tiina SaloiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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2 shared papersPhysiology

Katri Seppälä

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Sublethal immune resistance to parasites generates reaction-norm patterns indistinguishable from tolerance

Otto Seppälä, Ben Ashby

The paper shows that sublethal immune resistance can mimic tolerance in reaction-norm analysis, challenging the distinction between resistance and tolerance.

bioRxiv · Jul 3, 2026 · PreprintEvolutionary Biology

Intraspecific genetic variation modulates immune responses to acute heat exposure in an aquatic ectotherm

Maurine Neiman, Katri Seppälä, Dunja K. Lamatsch, Otto Seppälä

The paper examines how genetic variation within a snail species affects immune responses to heat stress, finding trait-specific and genotype-dependent immune suppression under heatwave conditions.

bioRxiv · Jun 5, 2026 · PreprintPhysiology

Transcriptome profiling of a multiuse model species Lymnaea stagnalis (Gastropoda) for ecoimmunological research

Otto Seppälä, Jean‐Claude Walser, Teo Cereghetti, Katri Seppälä, Tiina Salo, Coen M. Adema

The paper profiles the transcriptome of Lymnaea stagnalis to identify immune-related genes and their expression under various immune and environmental conditions.

bioRxiv · Sep 23, 2020 · PreprintGenomics