Author

Cole A. Lyman

Brigham Young UniversityORCID 0000-0001-7921-165XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:human· 1

Frequent Co-Authors

Gordon BroderickiD· 2 shared Matthew C. MorrisiD· 2 shared Antony Scerri· 1 shared Chris Cheadle· 1 shared Garry L. SpinkiD· 1 shared Hongbao CaoiD· 1 shared J. Tory Toole· 1 shared Spencer RichmaniD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersSystems Biology

Gordon BroderickORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintApr 26, 2022

Inflammation as a Silent Partner in Opioid Addiction: A Regulatory Logic Model

J. Tory Toole, Matthew C. Morris, Cole A. Lyman…·Gordon Broderick

The paper constructs a regulatory network model of 44 immune and neurotransmission mediators to show that inflammation is linked to chronic pain, depression, and opioid addiction through increased NF-kB and inflammatory signaling proteins.

DOI 10.1101/2022.04.26.489572

humanstatistical model

𝕏 PostBluesky

Systems BiologybioRxivPreprintNov 9, 2021

Attractor Landscapes as a Model Selection Criterion in Data Poor Environments

Cole A. Lyman, Spencer Richman, Matthew C. Morris…·Gordon Broderick

The paper introduces attractor landscapes as a model selection criterion for data-poor environments, reducing 18 immune response models to 7 with statistical significance.

2 citations

statistical modelbenchmarking

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