Yanmin Chen

The paper identifies ZMYM3 variants in 22 individuals with neurodevelopmental delay, showing recurrent mutations, phenotypic overlap, and functional effects, supporting ZMYM3 as a novel NDD gene.

This study demonstrates the feasibility of creating multi-dimensional genomic maps for juvenile idiopathic arthritis using limited patient samples and identifies epigenetic and genetic features associated with the disease.

The paper investigates chromatin landscapes and genetic risk loci in JIA by analyzing chromatin marks and transcription in neutrophils and CD4+ T cells, finding that risk loci show specific chromatin features and transcriptional activity.