Author

Witold K. Surewicz

Case Western Reserve UniversityORCID 0000-0001-7940-6027Unclaimed ORCID profile · follow to get notified of new preprints

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Biophysics· 1

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Approach:simulation· 1

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Brandon ShipleyiD· 1 shared Krystyna A. Surewicz· 1 shared Michael HinczewskiiD· 1 shared Raza Haider· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiophysics

Brandon ShipleyORCID

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1 paper

Recent·Most cited

BiophysicsProtein SciencePeer-reviewedSep 20, 2024

Pathological C-terminal phosphomimetic substitutions alter the mechanism of liquid-liquid phase separation of TDP-43 low complexity domain

Raza Haider, Brandon Shipley, Krystyna A. Surewicz…·Witold K. Surewicz

This study investigates how phosphomimetic substitutions at C-terminal sites of TDP-43's low complexity domain alter liquid-liquid phase separation, revealing a biphasic salt dependence and changes in phase separation mechanisms.

17 citations

humanprotein sequence

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