Author

Sayane Shome

Harvard UniversityORCID 0000-0001-7959-470XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Research Focus:protein design· 1

Frequent Co-Authors

Aashna Saraf· 1 shared Benjamin Roger Litterer· 1 shared Kejue JiaiD· 1 shared Robert L. JerniganiD· 1 shared Sripal Vajinepalli· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperBioinformatics

Aashna Saraf

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 28, 2026

Sequence-Based Prioritization of Promoter Regulatory Variants in Colorectal Cancer Using a DNA Foundation Model

Sripal Vajinepalli, Aashna Saraf, Sayane Shome

This paper uses a DNA foundation model to prioritize promoter regulatory variants in colorectal cancer, identifying high-impact variants enriched in cancer-related pathways and GWAS loci.

DOI 10.64898/2026.05.25.727528

humanDNA methylation

𝕏 PostBluesky

BioinformaticsbioRxivPreprintFeb 1, 2022

New Functions Identified for HIV gp120 with the New ProtSub Sequence Matching

Benjamin Roger Litterer, Sayane Shome, Kejue Jia, Robert L. Jernigan

The paper introduces a new sequence matching method, ProtSub, that incorporates structural information to identify novel functions for HIV gp120 proteins, showing improved accuracy over conventional methods.

DOI 10.1101/2022.02.01.478707

humanprotein sequence

𝕏 PostBluesky