Kejue Jia

An ancient monoaminergic signaling system coordinates contractility in a nerveless sponge

This study identifies an ancient monoaminergic system in sponges that coordinates contractility through tryptamine signaling, predating neurons.

Conserved and lineage-restricted gene regulatory programs modulate developmental cnidocyte specification in Nematostella vectensis.

The paper identifies conserved and lineage-specific gene regulatory programs involved in cnidocyte specification in Nematostella vectensis, revealing how novel transcription factors contribute to cnidocyte diversification.

Protein Language Model Performs Efficient Homology Detection

PLAST uses protein language models and discrete cosine transforms to efficiently detect homologs with high accuracy and speed.

New Functions Identified for HIV gp120 with the New ProtSub Sequence Matching

The paper introduces a new sequence matching method, ProtSub, that incorporates structural information to identify novel functions for HIV gp120 proteins, showing improved accuracy over conventional methods.

SeqStruct : A New Amino Acid Similarity Matrix Based on Sequence Correlations and Structural Contacts Yields Sequence-Structure Congruence

The paper introduces a new amino acid similarity matrix that improves sequence matching by incorporating structural information, resulting in better sequence-structure congruence.