Author

Annabell C. Segarra

University of Puerto Rico, Medical Sciences CampusORCID 0000-0001-7963-8290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2

Frequent Co-Authors

Amanda J. González-Segarra· 2 shared Andrea Mendez-Morales· 1 shared Carlos J. Rivero· 1 shared Enrique U. Pérez‐Cardona· 1 shared Iván G. Santiago-MarreroiD· 1 shared Jaime A. Freire· 1 shared José L. Agosto· 1 shared Raissa Menéndez‐Delmestre· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Amanda J. González-Segarra

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2 papers

Recent·Most cited

NeuroscienceScientific ReportsPeer-reviewedSep 26, 2025

Nandrolone alters the behavioral response to cocaine as well as striatal and cortical dopamine receptors of prepubertal male rats.

Jaime A. Freire, Carlos J. Rivero, Iván G. Santiago-Marrero…·Annabell C. Segarra

This study shows that nandrolone exposure before puberty in male rats reduces anxiety, alters cocaine-induced locomotor sensitization, and changes dopamine receptor expression in striatal and cortical regions.

DOI 10.1038/s41598-025-17890-6

ratexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 7, 2024

Cocaine sensitization in male rats requires activation of estrogen receptors

Raissa Menéndez‐Delmestre, José L. Agosto, Amanda J. González-Segarra, Annabell C. Segarra

This study shows that estradiol, not DHT, is required for cocaine sensitization in male rats, highlighting its role in cocaine-induced neuroplasticity.

2 citations

ratexperimental assay

𝕏 PostBluesky