Molecular BiologyJournal of Biological ChemistryPeer-reviewed
Consequences of alanine-126 mutations in helix-3 on structure and functions of Rad6 E2 ubiquitin-conjugating enzymes
Prakash Shukla, Dhiraj Prasad Sinha, Andrew M. Leng…·Mahesh B. Chandrasekharan
This study investigates how mutations at alanine-126 in helix-3 of Rad6 affect its ubiquitination activity and structural stability in yeast and human homologs.