BioinformaticsPLoS ONEPeer-reviewed
Structural Analysis of Recombinant AAV Vector Genomes at Single-Molecule Resolution
David Rouleau, Dimpal Lata, Serena Dollive…·Ify Iwuchukwu
The paper develops a pipeline to classify AAV genome structures at single-molecule resolution using long-read sequencing, revealing structural heterogeneity and its contributing factors.
DOI 10.1371/journal.pone.0339201