Natascha van Lieshout

This paper presents a high-quality de novo genome assembly of Chrysanthemum makinoi, a wild diploid ancestor of cultivated chrysanthemums, using long-read and short-read sequencing technologies.

The paper presents HuRI, a comprehensive human protein-protein interaction map, and demonstrates its utility in understanding cellular function and disease mechanisms.

This paper develops a deep mutational scanning framework to map functional missense variants in human genes and applies it to four proteins, identifying pathogenic variants and showing scalability to disease genes.