Systems BiologybioRxivPreprint
Tyrosine kinase inhibitors induce mitochondrial dysfunction during cardiomyocyte differentiation through alteration of GATA4-mediated networks
Qing Liu, Haodi Wu, Qing-Jun Luo…·Michael P. Snyder
This study shows that tyrosine kinase inhibitors cause mitochondrial dysfunction in cardiomyocytes by altering GATA4-mediated networks, and GATA4 overexpression can rescue these effects.
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