Variational inference accelerates accurate DNA mixture deconvolution
Mateusz Susik, Ivo F. Sbalzarini
This paper shows that variational inference methods like SVGD and VI can speed up DNA mixture deconvolution with minimal loss of accuracy.
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Technische Universität DresdenORCID 0000-0001-8133-6742Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Mateusz Susik, Ivo F. Sbalzarini
This paper shows that variational inference methods like SVGD and VI can speed up DNA mixture deconvolution with minimal loss of accuracy.
Mateusz Susik, Ivo F. Sbalzarini
The paper validates a Hamiltonian Monte Carlo genotyping algorithm on DNA mixtures, showing reliable likelihood ratios and proposing a new precision benchmark.
Mateusz Susik, Holger Schönborn, Ivo F. Sbalzarini
This paper introduces a Hamiltonian Monte Carlo algorithm with strict convergence criteria to reduce run-to-run variability in forensic DNA mixture deconvolution without increasing runtime.
Bevan L. Cheeseman, Ulrik Günther, Krzysztof Gonciarz…·Ivo F. Sbalzarini
This paper introduces an adaptive particle representation for fluorescence microscopy images to overcome storage and processing bottlenecks by replacing pixels with content-aware particles.