Second-order regulation: IFN-γ suppresses IL-17A-mediated neutrophilic inflammation.
Vijay Raaj Ravi, Sophia H. Maxfield, Emma N. Niszczak, Hannah Y. Kim, Olivia S. Harlow, Kalyn D. Whitehead, Anukul T. Shenoy
This study shows IFN-γ suppresses IL-17A-driven neutrophilic inflammation in the lungs via STAT1, revealing a regulatory interaction between TH1 and TH17 cells.
bioRxiv · Jan 6, 2026 · PreprintImmunology