Author

Arjan Kortholt

University of GroningenORCID 0000-0001-8174-6397Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 1

Frequent Co-Authors

Elisa GreggioiD· 2 shared Franz Y. HoiD· 2 shared Jean‐Marc TaymansiD· 2 shared Ahmed SolimaniD· 1 shared Alexander Marc ThouiniD· 1 shared Anna Memou· 1 shared Christian Johannes GloeckneriD· 1 shared Ciro IaccarinoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Elisa GreggioORCID

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2 papers

Recent·Most cited

NeuroscienceBiochemical JournalPeer-reviewedMay 14, 2026

Regulation between LRRK2 and PP2A signaling in cellular models of Parkinsons disease

Panagiotis S. Athanasopoulos, Anna Memou, Franz Y. Ho…·Arjan Kortholt

This study identifies a regulatory feedback loop between LRRK2 and PP2A phosphatases in Parkinson's disease, showing that LRRK2 phosphorylates PP2A to disrupt its function and contribute to neuronal death.

1 citation

humanstatistical model

𝕏 PostBluesky

NeuroscienceCell Death and DiseasePeer-reviewedOct 17, 2024

PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner

Lucia Iannotta, Rachel Fasiczka, Giulia Favetta…·Elisa Greggio

This study identifies PAK6 as a modifier of LRRK2 mutations, showing it rescues ciliogenesis defects in G2019S but not R1441C mutations.

5 citations

humanexperimental assay

𝕏 PostBluesky