Cell BiologybioRxivPreprint
KCa3.1 Drives Pro-Fibrotic Activation and Represents a Novel Therapeutic Target in Aortic Stenosis
Molly Whitfield, Saadia Aslam, João Goncalves De Sousa…·Katy Morgan Roach
This study shows KCa3.1 channels drive fibrosis in aortic stenosis by promoting myofibroblast contraction and collagen production, and inhibition with senicapoc reduces these effects.
DOI 10.64898/2026.04.30.720379