Molecular BiologybioRxivPreprint
Rhythmic variation in proteomics: challenges and opportunities for statistical power and biomarker identification
Matt P. Spick, C Isherwood, Lee A. Gethings…·Jonathan D. Johnston
This paper shows that time-of-day variation in proteomics increases Type II errors and recommends accounting for rhythmicity in study design to improve statistical power and reproducibility.
DOI 10.1101/2024.06.28.601121