Manuel Spitschan

Circadian multimodal physiological, ocular and behavioural data from a 40-hour forced-desynchrony protocol

The paper presents a multimodal dataset from a 40-hour forced-desynchrony protocol to study circadian rhythms and their effects on physiology, ocular function, and behavior.

Phasic pupil responses to melanopsin- and cone-directed stimulation remain stable across circadian time

The paper examines circadian modulation of pupil responses to different photoreceptor pathways and finds no support for circadian modulation of phasic pupil tracking.

The health-relevant architecture of the everyday light exposome

The paper assesses light exposure patterns in daily life and identifies gaps in meeting recommended illuminance levels, highlighting the need for interventions to improve health outcomes.

Sensor placement causes outcome-dependent bias in ambulatory light-exposure estimates

This study quantifies how chest and wrist placement of light dosimeters affects estimates of eye-level light exposure and derived metrics across different contexts and analytical scales.

Age-corrected model for predicting pupil diameter in real-world conditions from melanopic equivalent daylight illuminance

The paper develops an age-corrected model to predict pupil diameter from melanopic equivalent daylight illuminance in real-world conditions, showing it performs well compared to other models.

Photoreceptor-specific scene statistics reveal melanopic structure in natural environments

The paper quantifies melanopic input from natural scenes across different environments and photoreceptors, finding structured spatial variation and power-law patterns in melanopic luminance.

Audiovisual stimulation using wearable shutter glasses robustly evokes 40 Hz neuronal activity but does not modulate associative memory

This study validates the use of wearable shutter glasses to evoke 40 Hz neuronal activity but finds no effect on associative memory.

Analysis of human visual experience data

This paper provides a tutorial for analyzing visual experience datasets using reproducible workflows and the LightLogR R package, focusing on chronobiology and myopia research.

Associations between habitual light exposure-related behaviors and sleep timing and sleep complaints in an international community sample

This study examines how habitual light exposure-related behaviors affect sleep timing and complaints in a large international sample, finding that outdoor time and device use in bed have significant impacts.

Regulation of eye movements and pupil size in natural scenes

This study analyzes eye movement and pupil size in natural indoor and outdoor scenes, finding increased saccade metrics and pupil size in indoor environments initially, and different correlations between indoor and outdoor conditions.

Auxiliary data, quality assurance and quality control for wearable light loggers and optical radiation dosimeters

The paper develops auxiliary data frameworks and quality control strategies for wearable light loggers to improve data accuracy and interpretability in circadian research.

Delayed, Reduced and Redundant: Information Processing of Prediction Errors during Sleep

The paper analyzes prediction error processing during sleep using information-theoretic methods, finding reduced and redundant neural information with deeper sleep and REM.

dlmoR: An open-source R package for the dim-light melatonin onset (DLMO) hockey-stick method

dlmoR implements the hockey-stick method for DLMO estimation, showing high agreement with existing methods and revealing algorithmic limitations.

Collecting, detecting and handling non-wear intervals in longitudinal light exposure data

The paper collects and compares methods for detecting non-wear intervals in light exposure data from wearable devices.

Physiologically-relevant light exposure and light behaviour in Switzerland and Malaysia

This study compares light exposure and behaviour in Switzerland and Malaysia, finding cultural and geographical differences in light exposure patterns and the relationship between self-reported and objective measures.

Circadian timing does not modulate human temporal contrast sensitivity

This study investigates whether circadian timing affects human temporal contrast sensitivity and finds no evidence of circadian modulation in cone-mediated visual performance.

Sex and seasonal variations in melatonin suppression, and alerting response to light

This study examines how sex and seasonality affect melatonin suppression and alertness to light, finding sex differences and seasonal variations in light sensitivity.

40 Hz Steady-State Visually Evoked Potentials Recovered During Oscillating Transcranial Electrical Stimulation

The paper demonstrates that 40 Hz SSVEPs can be reliably measured during frequency-matched electrical brain stimulation, distinguishing neuronal activity from electrical artefacts.

Afternoon to early evening bright light exposure reduces later melatonin production in adolescents

This study finds that afternoon-early evening bright light exposure in adolescents reduces later evening melatonin production without affecting sleepiness or vigilance.

How to deal with darkness: Modeling and visualization of zero-inflated personal light exposure data on a logarithmic scale

The paper addresses zero-inflated personal light exposure data by comparing visualization methods and modeling approaches, finding that symlog scales and Tweedie distribution are effective for handling zero values in logarithmic contexts.

Lack of evidence for the contribution of cone photoreceptors to human melatonin suppression and alerting response to light at night

This study tests if cone photoreceptors affect melatonin suppression and alertness to light at night, finding no significant effect.

Non-linear effects of evening light exposure on cognitive performance

This study examines how different levels of melanopic illuminance affect cognitive performance and workload, finding non-linear relationships with both positive and negative effects at moderate and extreme light levels.

Joint infrared pupil images and near-corneal-plane spectral light exposure data under natural conditions across the adult lifespan

The paper presents a dataset of pupil size and spectral light exposure data collected under natural conditions across the adult lifespan to study retinal input variations.

Standardized and calibrated light stimuli via head-mounted displays for investigating the non-visual effects of light

This study uses VR head-mounted displays to deliver standardized light stimuli and finds melatonin suppression in 75% of participants.

Sneezing in response to bright light exposure: A case study in a photic sneezer

This study characterizes photic sneezing in response to natural and artificial light stimuli and finds that sudden increases in illuminance trigger sneezing, though artificial stimuli failed to induce it.

Inclusion, reporting and analysis of demographic variables in chronobiology and sleep research

The paper analyzes the reporting of demographic variables in sleep and chronobiology research over 40 years, finding that while age and sex are commonly reported, other variables are underreported.

Regulation of pupil size in natural vision across the human lifespan

This study investigates how pupil size changes with age and light conditions in natural environments using real-world data from 83 participants.

Temporal sensitivity for achromatic and chromatic flicker across the visual cortex

This study measures temporal sensitivity of visual cortex responses to achromatic and chromatic flicker stimuli across different cortical areas and eccentricities.

Power analysis for human melatonin suppression experiments

This paper presents a Bayesian framework and Shiny app for power analysis in melatonin suppression experiments, accounting for individual variability and experimental parameters.

Effects of calibrated blue-yellow (-S+) changes in light on the human circadian clock

This study investigates the impact of blue-yellow light changes on the human circadian clock and sleep, finding no significant effects under moderate light levels.