Author

Dominic Scalise

California Institute of TechnologyORCID 0000-0001-8218-1797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Kutay SesliiD· 1 shared Natalie KallishiD· 1 shared Phillip James DorseyiD· 1 shared Rebecca SchulmaniD· 1 shared Yue ZhaoiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperSynthetic Biology

Kutay SesliORCID

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2 papers

Recent·Most cited

Synthetic BiologyACS Chemical BiologyPeer-reviewedMay 28, 2026

Adverse Effects of UV-Exposure on DNA Strand Displacement Reactions

Kutay Sesli, Yue Zhao, Natalie Kallish, Dominic Scalise

This study identifies UV-shadowing as a source of errors in DNA strand displacement reactions and proposes a UV-free purification protocol to improve circuit performance.

DOI 10.1021/acschembio.5c00845

DNA methylationexperimental assay

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Synthetic BiologybioRxivPreprintFeb 26, 2022

Enabling spatiotemporal regulation within biomaterials using DNA reaction- diffusion waveguides

Phillip James Dorsey, Dominic Scalise, Rebecca Schulman

This paper designs DNA-based reaction-diffusion waveguides to enable spatiotemporal signal propagation in synthetic biomaterials, allowing for controlled biochemical communication.

2 citations

statistical model

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