Author

María Romina Girotti

Consejo Nacional de Investigaciones Científicas y TécnicasORCID 0000-0001-8235-3296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:deconvolution· 1 Approach:statistical model· 1

Frequent Co-Authors

Elmer A. FernándeziD· 2 shared Hugo Daniel LujániD· 2 shared Darío RochaiD· 1 shared Florencia VeigasiD· 1 shared Gabriel A. RabinovichiD· 1 shared Gabriel MoróniD· 1 shared Guadalupe NibeyroiD· 1 shared Laura Beatriz PratoiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Elmer A. FernándezORCID

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2 papers

Recent·Most cited

MHC-I binding affinity derived metrics fail to predict tumor specific neoantigen immunogenicity

Guadalupe Nibeyro, María Romina Girotti, Laura Beatriz Prato, Gabriel Morón, Hugo Daniel Luján, Elmer A. Fernández

The paper benchmarks neoantigen immunogenicity predictors and finds that MHC-I binding affinity and its derived metrics are insufficient to predict immunogenicity or tumor neoantigen burden as biomarkers.

bioRxiv · Mar 14, 2022 · PreprintBioinformatics

MIXTURE: an improved algorithm for immune tumor microenvironment estimation based on gene expression data.

Elmer A. Fernández, Yamil Damian Mahmoud, Florencia Veigas, Darío Rocha, Mónica Balzarini, Hugo Daniel Luján, Gabriel A. Rabinovich, María Romina Girotti

MIXTURE improves immune tumor microenvironment estimation by reducing overestimation of cell-type counts and improving accuracy in bulk RNA data.

bioRxiv · Aug 7, 2019 · PreprintBioinformatics