BioinformaticsbioRxivPreprint
MHC-I binding affinity derived metrics fail to predict tumor specific neoantigen immunogenicity
Guadalupe Nibeyro, María Romina Girotti, Laura Beatriz Prato…·Elmer A. Fernández
The paper benchmarks neoantigen immunogenicity predictors and finds that MHC-I binding affinity and its derived metrics are insufficient to predict immunogenicity or tumor neoantigen burden as biomarkers.
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