Stephan Ernst Baldus

This study shows that chronic PDGF signaling increases VSMC apoptosis in atherosclerotic plaques by promoting PI3K-dependent c-Myc expression and reducing Bcl-2, leading to plaque instability.

This study identifies a non-cell death role for MLKL in TGF-β receptor recycling and aortic integrity in Marfan syndrome.

This study shows vitamin K2 reduces ferroptosis-driven lipid peroxidation and slows aortic valve stenosis progression in both human and mouse models.

This study shows that Olfr2 promotes abdominal aortic aneurysm by enhancing CX3CR1-mediated monocyte recruitment through inflammatory pathways.

This study shows MPO enters endothelial cell nuclei, binds chromatin non-enzymatically, and regulates EndMT and EC fate through chromatin remodeling and interaction with ILF3.