Cancer BiologyAdvanced SciencePeer-reviewed
YAP promotes chromosomal instability by transcriptionally activating AJUBA through its super enhancer in breast cancer
Rui Zhang, Qingwen Huang, Zhuo Chen…·Daxing Xie
This study identifies YAP's role in promoting chromosomal instability in breast cancer by activating AJUBA through its super enhancer, leading to AURKA activation and aberrant mitosis.