Michael Margaliot A

The paper develops a mathematical model to study competition for shared translation resources among mRNAs and shows that adding mRNAs reduces pool density and total protein production.

The paper introduces a theoretical framework to model mRNA translation with ribosome competition, showing how parameter changes affect translation dynamics across a network.

The paper analyzes the periodic gain of the Ribosome Flow Model (RFM) and derives conditions for its optimality in translation elongation.