Author

Saghira Malik Sharif

Leeds Teaching Hospitals NHS TrustORCID 0000-0001-8331-3296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Daniel Shiloh MalawskyiD· 2 shared David A. van HeeliD· 2 shared Hilary C. MartiniD· 2 shared Ahsan KhaniD· 1 shared Ataf Hussain SabiriD· 1 shared Benjamin M. JacobsiD· 1 shared Chris GriffithsiD· 1 shared Dan MasoniD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Daniel Shiloh MalawskyORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Influence of autozygosity on common disease risk across the phenotypic spectrum

Daniel Shiloh Malawsky, Eva S. van Walree, Benjamin M. Jacobs, Teng Hiang Heng, Qin Huang, Ataf Hussain Sabir, Saadia Rahman, Saghira Malik Sharif, Ahsan Khan, Maša Umićević Mirkov, Hiroyuki Kuwahara, Xin Gao, Fowzan Sami Alkuraya, Daniëlle Posthuma, William G. Newman, , Hilary C. Martin

The paper investigates the association between autozygosity and common diseases in multiple cohorts, finding significant links to twelve diseases and estimating autozygosity's contribution to type 2 diabetes cases.

Cell · Sep 26, 2023Peer-reviewedGenetic & Genomic Medicine

Fine-scale population structure and demographic history of British Pakistanis

Elena Arciero, Sufyan Abid Dogra, Daniel Shiloh Malawsky, Massimo Mezzavilla, Theofanis Tsismentzoglou, Qin Qin Huang, Karen A. Hunt, Dan Mason, Saghira Malik Sharif, David A. van Heel, Eamonn G. Sheridan, John Wright, Neil Small, Shai Carmi, Mark Martin Iles, Hilary C. Martin

This study examines the population structure and demographic history of British Pakistanis, revealing strong recent structure and low effective population sizes due to endogamy and consanguinity.

Nature Communications · Dec 10, 2021Peer-reviewedGenomics