Eva S. van Walree

The paper identifies sex differences in genetic and biological factors contributing to ischaemic heart disease-depression comorbidity, finding higher genetic correlation in females and distinct risk factors by sex.

This study identifies shared genetic factors across eight cardiovascular diseases using large-scale genetic data, revealing clusters and pathways related to vascular biology and systemic risk factors.

The paper investigates the association between autozygosity and common diseases in multiple cohorts, finding significant links to twelve diseases and estimating autozygosity's contribution to type 2 diabetes cases.

DRUGSETS identifies therapeutic mechanisms by analyzing GWAS associations with drug and mechanism-of-action gene sets, revealing both established and novel targets across CNS and non-CNS phenotypes.