Massimo Mezzavilla

Photosynthesis regulation impacts carbon and nitrogen assimilation in the diazotrophic cyanobacterium Anabaena sp. PCC 7120

This study investigates how photosynthesis regulation affects carbon and nitrogen assimilation in Anabaena sp. PCC 7120 under varying environmental conditions.

The Neanderthal population history and the introgression landscape inferred from the UK Biobank

The paper uses UK Biobank data to infer Neanderthal population history and introgression patterns, finding divergence times, effective population sizes, and regions of selection.

GBRAP: A Comprehensive Database and Tool for Exploring Genomic Diversity Across All Domains of Life

GBRAP provides a database and tool for analyzing genomic diversity across all domains of life by offering curated genome statistics and visualization capabilities.

Relationship between Transposable Elements and behavioral traits: insights from six genetic isolates from North-Eastern Italy

The paper investigates the association between polymorphic transposable elements (TEs) and behavioral traits and BMI in six Italian genetic isolates, finding significant links to health-related phenotypes.

Worldwide patterns in mythology echo the human expansion out of Africa

This study combines genetic data and mythological motifs to show that population movements and cultural diffusion shaped the distribution of myths globally, with evidence dating back to 38,000 years ago.

Partitioning the genomic journey to becoming Homo sapiens

The paper identifies 56 recent functional variants in modern humans, 24 linked to brain functions and skull morphology, which did not introgress into Neanderthals.

Himalayan whole-genome sequences provide insight into population formation and adaptation

The paper presents whole-genome sequences from 16 Himalayan populations to study population structure, adaptation, and genetic history, revealing early population divergence, shared adaptive haplotypes, and recent gene flow.

Ancestral genetic components are consistently associated with the complex trait landscape in European biobanks

This study investigates the association between ancestral genetic components and complex traits in European biobanks, finding that these components contribute to trait variation and act as confounders.

Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization

Fine-scale population structure and demographic history of British Pakistanis

This study examines the population structure and demographic history of British Pakistanis, revealing strong recent structure and low effective population sizes due to endogamy and consanguinity.

Poking COVID-19: insights on genomic constraints among immune-related genes between Qatari and Italian populations

This study compares genomic variations in immune-related genes between Qatari and Italian populations to identify differences in selective pressures.

The landscape of autosomal-recessive pathogenic variants in European populations reveals phenotype-specific effects

The paper estimates carrier rates and risk of severe autosomal recessive disorders in European populations using exome sequences.

Establishment and equilibrium levels of deleterious mutations in large populations

The paper models mutation dispersion in populations, estimating selective advantages using Dunbar's number and observed mutation prevalence.

A transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans

This study creates a transcriptomic atlas of olfactory mucosae across species to show evolutionary patterns in odor detection capabilities.

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

This paper estimates narrow-sense heritability using identity-by-descent information in unrelated individuals and finds that IBD-based methods can capture rare variant contributions but are affected by stratification.

Continuity and admixture in the last five millennia of Levantine history from ancient Canaanite and present-day Lebanese genome sequences

This study analyzes ancient and modern genomes from the Levant to trace genetic continuity and admixture over five millennia, finding Canaanite-related ancestry and later Eurasian influences.

Genetic evidence for an origin of the Armenians from Bronze Age mixing of multiple populations

This study analyzes genome-wide variation in Armenians to show their origin from Bronze Age mixing of multiple populations and their genetic affinity to Neolithic Europeans.

Genetic landscape of populations along the Silk Road: admixture and migration patterns

This study analyzes the genetic structure of six Central Asian populations along the Silk Road, revealing admixture patterns and migration events linked to historical expansions.